Description
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Randomised double-blinded study
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4 treatment groups for each age group (18-49 and 60+)
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"Trivalent Darwin" formulation which includes A(H1N1), A(H3N2), and B/Victoria lineage strains
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"Trivalent Darwin" formulation with an additional antigenically distinct A(H3N2) strain
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"Trivalent Darwin" formulation with double the H3 antigen
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“Trivalent Tasmania” formulation composed of A(H1N1), B/Victoria lineage strains and an antigenically distinct A(H3N2) strain.
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Trial length
1 month
Participant age
Participant ages can range from 60+
Patient eligibility
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Healthy adult participants within the eligible age ranges
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Participants must not have received an influenza vaccine in 2024
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Participants must not have had a diagnosis of influenza within the past 12 months
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Female participants must NOT be pregnant
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Female participants must NOT be breastfeeding
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No history of immunosuppressive or immunodeficient conditions
2 onsite visits as well as 1 scheduled safety phone call is required from participants
*Travel is reimbursed for each visit
Follow-up inclusions
Objectives
To evaluate the safety and immunogenicity of an influenza vaccine formulation containing an additional H3 antigen.
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